Voltage-Sensing Phosphatases: Biophysics, Physiology, and Molecular Engineering
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چکیده
منابع مشابه
Functional diversity of voltage‐sensing phosphatases in two urodele amphibians
Voltage-sensing phosphatases (VSPs) share the molecular architecture of the voltage sensor domain (VSD) with voltage-gated ion channels and the phosphoinositide phosphatase region with the phosphatase and tensin homolog (PTEN), respectively. VSPs enzymatic activities are regulated by the motions of VSD upon depolarization. The physiological role of these proteins has remained elusive, and insig...
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ژورنال
عنوان ژورنال: Physiological Reviews
سال: 2018
ISSN: 0031-9333,1522-1210
DOI: 10.1152/physrev.00056.2017